CTNND1 anticorps

N° du produit ABIN7090818

Cet anticorps Lapin Monoclonal détecte spécifiquement CTNND1 dans IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CTNND1 anticorps (ABIN7090818)

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CTNND1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: G9H8

Détail du produit anti-CTNND1 anticorps

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human delta 1 Catenin

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CTNND1

Antigène: CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))

Autre désignation: delta 1 Catenin

Sujet:

Synonyms: p120, delta Catenin, Cadherin associated Src substrate, Cadherin-associated Src substrate, CAS, Catenin (cadherin associated protein) delta 1, Catenin delta 1, Catenin delta-1, CTND1_HUMAN, CTNND 1, CTNND, CTNND1, KIAA0384, P120 CAS, p120 catenin, P120 CTN, p120(cas), p120(ctn), P120CAS, P120CTN.

Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

ID gène: 1500

UniProt: O60716

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling